Wednesday, April 23, 2014

A Breakthrough?

A human-made compound in animal tests has been shown to reverse the process of artherosclerosis.
Specifically, the experiments showed that treatment with D-PDMP led to:
  • a drop in the animals' levels of so-called bad cholesterol or low-density lipoprotein, LDL; 
  • a drop in oxidized LDL, a particularly virulent form of fat that forms when LDL encounters free radicals. Oxidized LDL easily sticks to the walls of blood vessels, where it ignites inflammation, damaging the vessel walls and promoting the growth of fatty plaque; 
  • a surge in good cholesterol or high-density lipoprotein, HDL, known to counteract the effects of LDL by mopping it up; and 
  • a significant drop in triglycerides, another type of plaque-building fat.

  • The treatment also prevented fatty plaque and calcium deposits from building up inside the animals' vessels. These effects were observed in animals on a daily D-PDMP treatment even though they ate a diet made up of 20 percent triglycerides -- the human equivalent of eating a greasy burger for breakfast, lunch and dinner. In addition, the researchers say, D-PDMP appears to precision-target the worst byproducts of aberrant cell growth signaling, such as oxidized LDL and the activity of certain chemicals that fuel vessel inflammation, without altering cell growth itself.
    This all sounds like great stuff.  Furthermore, the compound has been well-tested in animals and hasn't produced any side effects even at 10 times the effective dose.

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