Wednesday, June 17, 2015

PROTACs on the Horizon

This new type of drug can target ALL disease-causing proteins. Yes, all of them. Specific varieties of it It works by tagging a specific protein for removal. The cell destroys the protein and the drug molecule is released to tag another bad protein. Most drugs today just latch on to the protein and block its function. High doses are needed to flood all the target proteins. A much lower dose of a PROTAC drug can be used because the molecules simply "catalyse" the destruction of the proteins.

I think this could be a game-changer.

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