Most COVID vaccine side effects due to placebo effect, metastudy finds.
A meta-analysis looking at data from 12 vaccine trials has concluded up to three-quarters of adverse events reported following COVID-19 vaccination can be attributed to the placebo effect. The researchers call for improved public health communication to inform people that many vaccine side effects can be attributed to what is known as the "nocebo effect."
The new research looked at data from 12 COVID-19 vaccine trials encompassing over 45,000 people. Over 35 percent of those in the trials receiving a placebo reported systemic side effects after the first dose, including fever, headache and fatigue. This compared to around 46 percent of those in active vaccine groups reporting similar side effects.
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