The researchers used implantable "drug factories" the size of a pinhead to deliver continuous, high doses of interleukin-2, a natural compound that activates white blood cells to fight cancer. The drug-producing beads can be implanted with minimally invasive surgery. Each contains cells engineered to produce interleukin-2 that are encased in a protective shell.
"We just administer once, but the drug factories keep making the dose every day, where it's needed until the cancer is eliminated," Veiseh said. "Once we determined the correct dose -- how many factories we needed -- we were able to eradicate tumors in 100% of animals with ovarian cancer and in seven of eight animals with colorectal cancer."
No comments:
Post a Comment